The Spanish firms appearing in the Fortune Global 500 list are shown below:

Source: Fortune Global 500, Fortune

Despite all the troubles in recent years banking groups Banco Bilbao Vizcaya Argentaria(BBVA) and Banco Santander(SAN) are still large enough to make it to this global ranking.

Related ETFs:

iShares MSCI Spain Capped Index (EWP)

The complete list of Spanish ADRs can  be found here.

Disclosure: Long BBVA, SAN